Best Pharmaceutical or Herb for Blunting Appetite – Q&A

Well, assuming you’re not talking about prescription types of drugs, I still have to say that the good old ephedrine/caffeine stack is one of the best appetite suppressants. In fact, early studies suggested that a majority (75% as I recall) of its effects were mediated via appetite suppression. I’d note that the appetite effects do wear off with time (although the thermogenic effects do not); adding the amino acid L-tyrosine (1 gram or so) seems to ‘re-activate’ the appetite suppressant effects.