Comments on: AMPK: Master Metabolic Regulator

By: lylemcd

lylemcd — Tue, 15 Nov 2011 21:53:31 +0000

Shifts in acute hormone and nutrient levels mostly. Things like blood glucose, insulin, etc.

By: Dave

Dave — Thu, 10 Nov 2011 14:59:10 +0000

If this is the wrong article to ask this question please correct me, but I’m wondering how does the body “know” whether it is overfeeding or under-eating.
The obvious answer is when the person is consuming more/less calories than his maintenance level, but that definition would only apply to a certain time-frame. How does the body know that in real time?
Also, does the reaction differ between various macro-nutrient ratios provided sufficient protein consumption? (ie. fat to carbs ratio)

By: Paul Brewer-Jensen

Paul Brewer-Jensen — Wed, 20 Jul 2011 22:01:04 +0000

Sleep is the drug you are looking for.
http://www.jneurosci.org/content/30/26/9007.abstract
Go to bed hungry and wake up not hungry thanks to the sleep induced increase of ATP in the resting brain and the concurrent drop in AMPK in said organ.

By: Zach

Zach — Tue, 17 May 2011 22:06:05 +0000

Thank you for this helpful article